CCDC36 Antibody (YA8739)(PBS only)
(Synonyms: CT74)CCDC36 Antibody (YA8739) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC36.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
CCDC36 Antibody (YA8739) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC36.
-
Host Mouse
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 64.9 kDa
Full length human recombinant protein of human CCDC36 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
CCDC36 is required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance
-
Subcellular Localization
Chromosome
-
Isoforms & Post-Translational Modification
Q8IYA8 has three isomers: Q8IYA8-1: 66343 Da (predicted); Q8IYA8-2: 64264 Da (predicted); Q8IYA8-3: 23196 Da (predicted).
-
Subunit
Part of the MCD recombinosome complex, at least composed of IHO1, REC114 and MEI4 (By similarity)
-
SwissProt ID
-
Synonyms
CT74
Documentation
Powered by Bioz
