CD24 Antibody (YA7734)
(Synonyms: CD24, CD24A, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen)CD24 Antibody (YA7734) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD24.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP
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Reactivity :
Human
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Formulation:
Supplied in PBS(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:20-50 |
Product Details
CD24 Antibody (YA7734) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD24.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 31-45 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 8 kDa
A synthesized peptide derived from human CD24
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity[1].
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells
Induction: Expression is lost when primary B-cells are induced to differentiate in antibody-forming cells -
Isoforms & Post-Translational Modification
P25063 has two isomers: P25063-1: 8083 Da (predicted); P25063-2: 12968 Da (predicted).
Extensively O-glycosylated -
Subunit
Interacts with LYN and FGR in a cell-type specific manner
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SwissProt ID
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Synonyms
CD24, CD24A, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen
Documentation
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