CDCA7L Antibody (YA7974)(PBS only)

Cat. No.: HY-P88290A: Fiche technique User Guide for Antibodies
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CDCA7L Antibody (YA7974) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDCA7L.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

CDCA7L Antibody (YA7974) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDCA7L.

Host

Mouse

Masse moléculaire

Predicted band size: 52 kDa

Species Reactivity

Human

SwissProt ID

Q96GN5

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-337 of human CDCA7L produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Pureté	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1

Subcellular Localization：Cytoplasm,Nucleus

Expression：
Tissue_Specificity: Ubiquitous. Overexpressed in medulloblastoma
Induction: By MYC overexpression in a concentration dependent manner in neuroblastoma cell line

Isoforms & Post-Translational Modification：Q96GN5 has four isomers: Q96GN5-1: 52206 Da (predicted); Q96GN5-2: 52078 Da (predicted); Q96GN5-4: 48309 Da (predicted); Q96GN5-5: 46779 Da (predicted).
Phosphorylation increases its interaction with PSIP1

Subunit：Interacts with MYC (PubMed:15994933, PubMed:16829576)

Synonyms

JPO2; R1; RAM2

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/vero-c1008-cell.html [Content Brief]