CISD2 Antibody (YA8794)(PBS only)
(Synonyms: ERIS; Miner1; NAF-1; WFS2; ZCD2)CISD2 Antibody (YA8794) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CISD2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
CISD2 Antibody (YA8794) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CISD2.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
Full length human recombinant protein of human CISD2 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CISD2 is a Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy
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Subcellular Localization
Endoplasmic reticulum membrane,Mitochondrion outer membrane
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Expression
Tissue_Specificity: Testis, small intestine, kidney, lung, brain, heart, pancreas and platelets -
Isoforms & Post-Translational Modification
Q8N5K1: 135 amino acids, molecular weight 15278 Da.
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Subunit
Homodimer
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SwissProt ID
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Synonyms
ERIS; Miner1; NAF-1; WFS2; ZCD2
Documentation
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