CLPTM1 Antibody (YA2521)(PBS only)

Cat. No.: HY-P82776A: Data Sheet User Guide for Antibodies
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CLPTM1 Antibody (YA2521) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLPTM1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명
References

제품 설명

CLPTM1 Antibody (YA2521) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLPTM1.

Host

Rabbit

분자량

Predicted band size: 76 kDa;

Observed band size: 90 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O96005

Gene ID

1209 [NCBI]

Immunogen

A synthetic peptide of human CLPTM1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate (By similarity). Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one (By similarity). Required for efficient glycosylphosphatidylinositol (GPI) inositol deacylation in the ER, which is a crucial step to switch GPI-anchored proteins (GPI-APs) from protein folding to transport states (PubMed:29255114). May play a role in T-cell development (By similarity)

Subcellular Localization：Membrane; Multi-pass membrane protein

Expression：
Tissue_specificity:Widely expressed

Isoforms & Post-Translational Modification：O96005 has 3 isomers: O96005-1: 76097 Da (predicted); O96005-3: 65597 Da (predicted); O96005-4: 75178 Da (predicted).

Research Field

Cell Biology

Synonyms

Cleft lip and palate transmembrane protein 1

각종 서류

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/mkn-45-cell.html [Content Brief]