Dopamine beta Hydroxylase Antibody (YA10031)
(Synonyms: Dopamine beta-hydroxylase, Dopamine beta-monooxygenase)Dopamine beta Hydroxylase Antibody (YA10031) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to Dopamine beta Hydroxylase.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
Dopamine beta Hydroxylase Antibody (YA10031) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to Dopamine beta Hydroxylase.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 70-75 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 69 kDa
Synthetic peptide corresponding to human Dopamine beta Hydroxylase protein.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Dopamine beta Hydroxylase catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters
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Subcellular Localization
Cytoplasmic vesicle, secretory vesicle lumen; Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen; Secreted
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Expression
Induction: Activity is enhanced by nerve growth factor (in superior cervical ganglia and adrenal medulla). Trans-synaptic stimulation with reserpine, acetylcholine and glucocorticoids. -
Isoforms & Post-Translational Modification
Dopamine beta Hydroxylase has an amino acid length of 617, molecular weight is 69065 Da.
N-glycosylated. -
Subunit
Homotetramer; composed of two disulfide-linked dimers
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SwissProt ID
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Synonyms
Dopamine beta-hydroxylase, Dopamine beta-monooxygenase
Documentation