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Dynein Intermediate Chain 1 Antibody (YA3374)

(Synonyms: DNAI1; ICS; Immotile cilia syndrome 1; ICS1; CILD1; PCD)

Dynein Intermediate Chain 1 Antibody (YA3374) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dynein Intermediate Chain 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • Conjugation:
    Non-conjugated
  • Dynein Intermediate Chain 1 Antibody (YA3374) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

Dynein Intermediate Chain 1 Antibody (YA3374) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dynein Intermediate Chain 1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 79 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 79 kDa
Species Reactivity Database
Immunogen

A synthesized peptide derived from human Dynein intermediate chain 1 aa1-240/699.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Dynein Intermediate Chain 1 is a Part of the dynein complex of respiratory cilia

  • Subcellular Localization

    Dynein axonemal particle; Cytoplasm, cytoskeleton, cilium axoneme

  • Expression


    Tissue_specificity:Expressed in respiratory ciliated cells (at protein level)

  • Isoforms & Post-Translational Modification

    Q9UI46 has 2 isomers: Q9UI46-1: 79283 Da (predicted); Q9UI46-2: 19284 Da (predicted).

  • Subunit

    Consists of at least two heavy chains and a number of intermediate and light chains. Interacts with BICD2 (PubMed:23664119). Interacts with CFAP45 and CFAP52 (PubMed:33139725). Interacts with CFAP53 (By similarity)

  • SwissProt ID

    Q9UI46

  • Gene ID
    27019 [NCBI]
  • Synonyms

    DNAI1; ICS; Immotile cilia syndrome 1; ICS1; CILD1; PCD

  • Research Field

    Cell Biology

Dynein Intermediate Chain 1 Antibody (YA3374) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Dynein Intermediate Chain 1 Antibody (YA3374) Product Image
    1/16
  • Dynein Intermediate Chain 1 Antibody (YA3374) Product Image