EIF3H Antibody (YA6552)
(Synonyms: eIF-3-gamma antibody; eIF3 gamma antibody; eIF3 p40 antibody; eIF3 p40 subunit antibody; eIF3h antibody; EIF3H_HUMAN antibody; EIF3S3 antibody; Eukaryotic translation initiation factor 3 subunit 3 antibody; Eukaryotic translation initiation factor 3 subunit H antibody; MGC102958 antibody; )EIF3H Antibody (YA6552) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EIF3H.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:200 |
Product Details
EIF3H Antibody (YA6552) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EIF3H.
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Host Mouse
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 40 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 40 kDa
Recombinant protein within human EIF3H aa 1-352 / 352.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EIF3H component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression[1][2][3].
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Subcellular Localization
Cytoplasm
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Subunit
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M
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SwissProt ID
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Synonyms
eIF-3-gamma antibody; eIF3 gamma antibody; eIF3 p40 antibody; eIF3 p40 subunit antibody; eIF3h antibody; EIF3H_HUMAN antibody; EIF3S3 antibody; Eukaryotic translation initiation factor 3 subunit 3 antibody; Eukaryotic translation initiation factor 3 subunit H antibody; MGC102958 antibody;
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