FANCA Antibody (YA2112)

Cat. No.: HY-P82367: Data Sheet COA
SDS
User Guide for Antibodies
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FANCA Antibody (YA2112) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FANCA.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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FANCA Antibody (YA2112) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

FANCA Antibody (YA2112) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FANCA.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 163 kDa;

Observed band size: 163 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O15360

Gene ID

2175 [NCBI]

Immunogen

A synthesized peptide derived from human FANCA aa1-130/1455.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:40

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability

Subcellular Localization：Nucleus; Cytoplasm

Isoforms & Post-Translational Modification：O15360 has 3 isomers: O15360-1: 162775 Da (predicted); O15360-2: 32984 Da (predicted); O15360-3: 159083 Da (predicted).
Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H

Subunit：Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA . In complex with FANCF, FANCG and FANCL, but not with FANCC, nor FANCE, interacts with HES1; this interaction may be essential for the stability and nuclear localization of FA core complex proteins. The complex with FANCC and FANCG may also include EIF2AK2 and HSP70. Interacts with FAAP20/C1orf86; interaction is direct

RRID

AB_3104476

Database

Entrez Gene: 2175 Human

SwissProt: O15360 Human

OMIM: 227650 Human

Research Field

Synonyms

FA 1; FA; FA H; FA1; FAA; FACA; FAH; Fanca; FANCH

Documentation

Select Batch:

Data Sheet (258 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/hel-92-1-7-cell.html [Content Brief]

FANCA Antibody (YA2112) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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FANCA Antibody (YA2112)

FANCA Antibody (YA2112) Featured Recommendations:

Product Detail

Background

Documentation

References

FANCA Antibody (YA2112) Related Classifications

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