country

Change Language

Country or Region:

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P87475

FPGS Antibody (YA7162)

FPGS Antibody (YA7162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FPGS.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot
Dilution Ratio	1:1000-2000

Description

FPGS Antibody (YA7162) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FPGS.

Host Rabbit
Clonality Recombinant
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 60kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 65kDa

Immunogen

A synthesized peptide derived from human FPGS

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

FPGS catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates
Subcellular Localization

Mitochondrion inner membrane,Mitochondrion matrix,Cytoplasm
Isoforms & Post-Translational Modification

Q05932 has four isomers: Q05932-1: 64609 Da (predicted); Q05932-2: 60167 Da (predicted); Q05932-3: 59174 Da (predicted); Q05932-4: 61562 Da (predicted).
Subunit

Monomer
SwissProt ID

Q05932