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GANAB Antibody (YA6579)

(Synonyms: Alpha glucosidase II alpha subunit antibody; Alpha-glucosidase 2 antibody; G2AN antibody; GANAB antibody; GANAB_HUMAN antibody; Glu II antibody; Glucosidase alpha neutral AB antibody; Glucosidase II alpha antibody; Glucosidase II subunit alpha antibody; GluII antibody; Alpha glucosidase II alpha subunit antibody; Alpha-glucosidase 2 antibody; G2AN antibody; GANAB antibody; GANAB_HUMAN antibody; Glu II antibody; Glucosidase alpha neutral AB antibody; Glucosidase II alpha antibody; Glucosidase II subunit alpha antibody; GluII antibody; KIAA0088 antibody; Neutral alpha glucosidase AB antibody; Neutral alpha glucosidase AB precursor antibody; Neutral alpha-glucosidase AB antibody; )
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GANAB Antibody (YA6579) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GANAB.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IF-Tissue, IP

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • GANAB Antibody (YA6579) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
IF-Tissue Info
IF-Tissue: Immunofluorescence-Tissue
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:1000-1:5000 1:1000 1:200 1-2μg/sample

Product Details

Description

GANAB Antibody (YA6579) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GANAB.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 107 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 107 kDa
Immunogen

Recombinant protein within human GANAB aa 29-450.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    GANAB is a Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia[1][2].

  • Subcellular Localization

    Endoplasmic reticulum,Golgi apparatus,Melanosome

  • Expression


    Tissue_Specificity: Detected in placenta (PubMed:3881423). Isoform 1 and isoform 2 are expressed in the kidney and liver (PubMed:27259053)

  • Isoforms & Post-Translational Modification

    Q14697 has three isomers: Q14697-1: 106874 Da (predicted); Q14697-2: 109438 Da (predicted); Q14697-3: 5673 Da (predicted).

  • Subunit

    Heterodimer of a catalytic alpha subunit (GANAB) and a beta subunit (PRKCSH) (PubMed:10929008)

  • SwissProt ID

    Q14697

  • Gene ID
    23193 [NCBI]
  • Synonyms

    Alpha glucosidase II alpha subunit antibody; Alpha-glucosidase 2 antibody; G2AN antibody; GANAB antibody; GANAB_HUMAN antibody; Glu II antibody; Glucosidase alpha neutral AB antibody; Glucosidase II alpha antibody; Glucosidase II subunit alpha antibody; GluII antibody; Alpha glucosidase II alpha subunit antibody; Alpha-glucosidase 2 antibody; G2AN antibody; GANAB antibody; GANAB_HUMAN antibody; Glu II antibody; Glucosidase alpha neutral AB antibody; Glucosidase II alpha antibody; Glucosidase II subunit alpha antibody; GluII antibody; KIAA0088 antibody; Neutral alpha glucosidase AB antibody; Neutral alpha glucosidase AB precursor antibody; Neutral alpha-glucosidase AB antibody;

GANAB Antibody (YA6579) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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