GLS2 Antibody (YA7756)(PBS only)
(Synonyms: GA; GLS; hLGA; LGA)GLS2 Antibody (YA7756) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLS2.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:2000-3000 | 1:2000-2500 |
Product Details
GLS2 Antibody (YA7756) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLS2.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 66.8 kDa
Full length human recombiant protein of human GLS2 produced in E.coli.
Affinity purified
Non-conjugated
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GLS2 plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation
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Subcellular Localization
Mitochondrion
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Expression
Tissue_Specificity: Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas
Induction: Up-regulated by P53 (at protein and mRNA level) under both stressed and non-stressed conditions -
Isoforms & Post-Translational Modification
Q9UI32 has two isomers: Q9UI32-1: 66323 Da (predicted); Q9UI32-2: 23055 Da (predicted).
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Subunit
Homotetramer, dimer of dimers (Probable)
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SwissProt ID
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Synonyms
GA; GLS; hLGA; LGA
Documentation
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