GLS2 Antibody (YA7756)(PBS only)

Cat. No.: HY-P88072A: Data Sheet User Guide for Antibodies
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GLS2 Antibody (YA7756) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLS2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

GLS2 Antibody (YA7756) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLS2.

Host

Mouse

Molecular Weight

Predicted band size: 66.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9UI32

Immunogen

Full length human recombiant protein of human GLS2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-3000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:2000-2500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation

Subcellular Localization：Mitochondrion

Expression：
Tissue_Specificity: Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas
Induction: Up-regulated by P53 (at protein and mRNA level) under both stressed and non-stressed conditions

Isoforms & Post-Translational Modification：Q9UI32 has two isomers: Q9UI32-1: 66323 Da (predicted); Q9UI32-2: 23055 Da (predicted).

Subunit：Homotetramer, dimer of dimers (Probable)

Synonyms

GA; GLS; hLGA; LGA

Documentation

User Guide for Antibodies (1077 KB)