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HARS Antibody (YA977)

(Synonyms: HRS; CMT2W; USH3B)

HARS Antibody (YA977) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HARS.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB

  • Reactivity :

    Human, Mouse, Monkey

  • Formulation:

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Conjugation:
    Non-conjugated
  • HARS Antibody (YA977) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

HARS Antibody (YA977) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HARS.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Monkey
  • Observed Molecular Weight
    Observed band size: 57 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 57 kDa
Species Reactivity Database
Immunogen

Purified recombinant human HARS protein fragments expressed in E.coli.

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    HARS catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance[1][2].

  • Subcellular Localization

    Cytoplasm

  • Expression


    Tissue_specificity:brain, heart, liver and kidneys

  • Isoforms & Post-Translational Modification

    P12081 has 4 isomers: P12081-1: 57411 Da (predicted); P12081-2: 52720 Da (predicted); P12081-3: 50156 Da (predicted); P12081-4: 54847 Da (predicted).

  • Subunit

    Homodimer

  • SwissProt ID

    P12081

  • Gene ID
    23438 [NCBI]
  • Synonyms

    HRS; CMT2W; USH3B

  • Research Field

    Immunology

HARS Antibody (YA977) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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