2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. HARS Antibody (YA977)

HARS Antibody (YA977) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HARS.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

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  • Beschreibung

  • Verweise

Beschreibung

HARS Antibody (YA977) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HARS.
Host

Mouse
Clonality

Monoclonal
Molekulargewicht
Predicted band size: 57 kDa;
Observed band size: 57 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Monkey
SwissProt ID
Gene ID
Immunogen

Purified recombinant human HARS protein fragments expressed in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Reinheit Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Versand

Shipping with blue ice.
Background
Function：Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP) (PubMed:29235198). Plays a role in axon guidance (PubMed:26072516)
Subcellular Localization：Cytoplasm
Expression：
Tissue_specificity:brain, heart, liver and kidneys
Isoforms & Post-Translational Modification：P12081 has 4 isomers: P12081-1: 57411 Da (predicted); P12081-2: 52720 Da (predicted); P12081-3: 50156 Da (predicted); P12081-4: 54847 Da (predicted).
Subunit：Homodimer
Database

Entrez Gene: 23438 Human ; 70791 Mouse

SwissProt: P49590 Human ; Q99KK9 Mouse

OMIM: 600783 Human

Research Field

Immunology
Synonyms
HRS; CMT2W; USH3B
Dokumentation
User Guide for Antibodies (1077 KB)
Verweise

HARS Antibody (YA977) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HARS Antibody (YA977)
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HY-P81278
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