HTR3A Antibody (YA4037)

製品番号: HY-P84340: データシート SDS COA User Guide for Antibodies
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HTR3A Antibody (YA4037) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HTR3A.

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容量	価格（税別）	在庫状況	数量
10 μL	$96	在庫あり	Estimated Time of Arrival: December 31
50 μL	$252	在庫あり	Estimated Time of Arrival: December 31
100 μL	$408	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
説明
参考文献

製品説明

HTR3A Antibody (YA4037) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HTR3A.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 55 kDa;

Observed band size: 55 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P46098

Gene ID

3359 [NCBI]

Immunogen

Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:500
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

純度	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2a

Appearance

Solution

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Verification Image

ALL FC ICC

Flow cytometric analysis of 1X10^6 Hela cells labeling HTR3A Antibody(HY-P84340
Immunofluorescence analysis of Hela cells labeling HTR3A antibody (HY-P84340) at 1/50 dilution. Cells were fixed in 4% paraformaldehyde for 15 minutes at room temperature

Background

Function：Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

Subcellular Localization：Postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein

Expression：
Tissue_specificity:Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta

Isoforms & Post-Translational Modification：P46098 has 5 isomers: P46098-1: 55280 Da (predicted); P46098-2: 58388 Da (predicted); P46098-3: 53763 Da (predicted); P46098-4: 55894 Da (predicted); P46098-5: 59002 Da (predicted).

Subunit：Forms homopentameric as well as heteropentameric serotonin-activated cation-selective channel complexes with HTR3B or HTR3C or HTR3D or HTR3E. The homomeric complex is functional but exhibits low conductance with modified voltage dependence, and decreased agonist and antagonist affinity. Heteropentameric complexes display properties which resemble that of neuronal serotonin-activated channels in vivo (PubMed:10521471, PubMed:15809299, PubMed:17392525, PubMed:9950429). Interacts with RIC3 (PubMed:15809299)

RRID

AB_3718886

Synonyms

HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R

ドキュメンテーション

Select Batch:

データシート (258 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/u-937-cell.html [Content Brief]