Kallikrein 8 Antibody (YA6901)

製品番号: HY-P87213: データシート SDS COA User Guide for Antibodies
FAQs
Technical Support

Kallikrein 8 Antibody (YA6901) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Kallikrein 8.

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容量	価格（税別）	在庫状況	数量
20 μL	$125	在庫あり	Estimated Time of Arrival: December 31
50 μL	$200	在庫あり	Estimated Time of Arrival: December 31
100 μL	$320	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Kallikrein 8 Antibody (YA6901) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Kallikrein 8.

Host

Rabbit

Clonality

Recombinant,Monoclonal

分子量

Predicted band size：28 kDa;

Observed band size: 35 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O60259

Immunogen

Recombinant protein within human Kallikrein 8 aa 161-260/260.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200

純度	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury

Subcellular Localization：Secreted,Cytoplasm

Expression：
Tissue_Specificity: Isoform 1 is predominantly expressed in the pancreas. Isoform 2 is expressed in adult brain and hippocampus. Isoform 1 and isoform 2 are found in fetal brain and placenta. Detected in salivary gland, uterus, thymus, breast, testis and kidney but not in spleen, liver, lung or normal ovarian tissue. Displays an 11.5-fold increase in Alzheimer disease hippocampus compared to controls and is overexpressed in some ovarian carcinomas. Expressed at low levels in normal skin while high levels are found in psoriasis vulgaris, seborrheic keratosis, lichen planus and squamous cell carcinoma skin samples. Expressed in the keratinocytes

Isoforms & Post-Translational Modification：O60259 has four isomers: O60259-1: 28048 Da (predicted); O60259-2: 32966 Da (predicted); O60259-3: 12719 Da (predicted); O60259-4: 3653 Da (predicted).

Subunit：Interacts with SPINK9

Synonyms

Brain serine protease 1 antibody

ドキュメンテーション

Select Batch:

データシート (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Kallikrein 8 Antibody (YA6901) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Kallikrein 8 Antibody (YA6901)

Product Detail

Background

説明

Kallikrein 8 Antibody (YA6901) 関連分類

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