KLC1 Antibody (YA2363)

Cat. No.: HY-P82618: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

KLC1 Antibody (YA2363) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KLC1.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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KLC1 Antibody (YA2363) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

KLC1 Antibody (YA2363) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KLC1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 65 kDa;

Observed band size: 65 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q07866

Gene ID

3831 [NCBI]

Immunogen

A synthesized peptide derived from human KLC1 aa501-573.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
FC FC: Flow Cytometry	1:50-1:100
IP IP: Immunoprecipitation	1:50

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 10mM phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (PubMed:21385839). The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity)

Subcellular Localization：Cell projection, growth cone; Cytoplasmic vesicle; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:Found in a variety of tissues. Mostly abundant in brain and spine

Isoforms & Post-Translational Modification：Q07866 has 10 isomers: Q07866-1: 65310 Da (predicted); Q07866-2: 63816 Da (predicted); Q07866-3: 64319 Da (predicted); Q07866-4: 71996 Da (predicted); Q07866-5: 69967 Da (predicted); Q07866-6: 71006 Da (predicted); Q07866-7: 66292 Da (predicted); Q07866-8: 62826 Da (predicted); Q07866-9: 72398 Da (predicted); Q07866-10: 69765 Da (predicted).
Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles

Subunit：Oligomeric complex composed of two heavy chains and two light chains. Interacts (via TPR repeats) with TOR1A; the interaction associates TOR1A with the kinesin oligomeric complex (PubMed:14970196).

Database

Entrez Gene: 3831 Human ; 171041 Rat

SwissProt: Q07866 Human ; O88447 Mouse ; P37285 Rat

OMIM: 600025 Human

Research Field

Signal Transduction

Synonyms

Kinesin2; KLC; Klc1; KNS2; KNS2A

Documentation

Select Batch:

Data Sheet (235 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/hepg2-cell.html [Content Brief]

KLC1 Antibody (YA2363) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KLC1 Antibody (YA2363)

KLC1 Antibody (YA2363) Featured Recommendations:

Product Detail

Background

Documentation

References

KLC1 Antibody (YA2363) Related Classifications

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