LLGL1 Antibody (YA3043)
(Synonyms: DLG4; HUGL; LLGL; Lgl1; Mgl1; HUGL1; HUGL-1)LLGL1 Antibody (YA3043) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LLGL1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP
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Reactivity :
Human
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:20 |
Product Details
LLGL1 Antibody (YA3043) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LLGL1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 115 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 115 kDa
Recombinant protein of human LLGL1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LLGL1 is a Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane
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Subcellular Localization
Early endosome membrane; Golgi apparatus, trans-Golgi network membrane; Golgi apparatus membrane; Cell projection, axon; Cytoplasm, cytoskeleton
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Expression
Tissue_specificity:Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease -
Subunit
Associated with nonmuscle myosin II heavy chain. Interacts with PRKCI/aPKC, PARD6B/Par-6 and PARD6A.
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SwissProt ID
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Synonyms
DLG4; HUGL; LLGL; Lgl1; Mgl1; HUGL1; HUGL-1
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Research Field
Neuroscience
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