MASP-3 Antibody (YA8891)
(Synonyms: Complement factor MASP 3, CRARF, CRARF1, MASP, MASP 1, MASP1, PRSS5, RaRF, Serine protease 5)
Based on 1 Customer Validation
MASP-3 Antibody (YA8891) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MASP-3.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:100-1000 |
Product Details
MASP-3 Antibody (YA8891) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MASP-3.
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Host Mouse
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Species Reactivityhuman
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Calculated Molecular Weight Predicted band size: 107 kDa
OMIM: 600521
A synthesized peptide derived from human MASP-3.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
MASP-3 is a Precursor of a serum protease that activates the complement pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Protein of the plasma which is primarily expressed by liver. -
Isoforms & Post-Translational Modification
MASP-3 has 4 isoforms, P48740-1: amino acid length is 699, molecular weight is 79247 Da (predicted); P48740-2: amino acid length is 728, molecular weight is 81860 Da (predicted); P48740-3: amino acid length is 380, molecular weight is 43640 Da (predicted); P48740-4: amino acid length is 615, molecular weight is 68918 Da (predicted).
Autoproteolytic processing of the proenzyme produces the active enzyme composed on the heavy and the light chain held together by a disulfide bond -
Subunit
Homodimer.
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SwissProt ID
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Synonyms
Complement factor MASP 3, CRARF, CRARF1, MASP, MASP 1, MASP1, PRSS5, RaRF, Serine protease 5
Documentation
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