MGARP Antibody (YA8833)(PBS only)

(Synonyms: C4orf49; CESP-1; HUMMR; OSAP)

MGARP Antibody (YA8833) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MGARP.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500-800

Product Details

Description

MGARP Antibody (YA8833) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MGARP.

  • Host Mouse
  • Species Reactivity
    Human
Immunogen

Full length human recombinant protein of human MGARP produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MGARP plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology. Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons

  • Subcellular Localization

    Mitochondrion,Mitochondrion outer membrane,Mitochondrion inner membrane

  • Expression


    Tissue_Specificity: Expressed in the brain, adrenal gland and corneal endothelium (CE). Expressed in steroid-producing cells of the ovary and testis (at protein level). Expressed in steroid-producing cells of the ovary and testis. Weakly expressed in placenta. Expressed in corneal endothelial cells

  • Isoforms & Post-Translational Modification

    Q8TDB4: 240 amino acids, molecular weight 25390 Da.

  • Subunit

    Interacts with RHOT1/Miro-1, TRAK1/OIP106 and TRAK2/GRIF1 (By similarity)

  • SwissProt ID

    Q8TDB4

  • Synonyms

    C4orf49; CESP-1; HUMMR; OSAP

MGARP Antibody (YA8833)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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