MGARP Antibody (YA8833)(PBS only)
(Synonyms: C4orf49; CESP-1; HUMMR; OSAP)MGARP Antibody (YA8833) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MGARP.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
MGARP Antibody (YA8833) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MGARP.
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Host Mouse
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Species ReactivityHuman
Full length human recombinant protein of human MGARP produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MGARP plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology. Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons
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Subcellular Localization
Mitochondrion,Mitochondrion outer membrane,Mitochondrion inner membrane
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Expression
Tissue_Specificity: Expressed in the brain, adrenal gland and corneal endothelium (CE). Expressed in steroid-producing cells of the ovary and testis (at protein level). Expressed in steroid-producing cells of the ovary and testis. Weakly expressed in placenta. Expressed in corneal endothelial cells -
Isoforms & Post-Translational Modification
Q8TDB4: 240 amino acids, molecular weight 25390 Da.
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Subunit
Interacts with RHOT1/Miro-1, TRAK1/OIP106 and TRAK2/GRIF1 (By similarity)
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SwissProt ID
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Synonyms
C4orf49; CESP-1; HUMMR; OSAP
Documentation