NAT-2 Antibody
(Synonyms: Aac2, Nat2, Arylamine N-acetyltransferase 2, Arylamide acetylase 2, N-acetyltransferase type 2, N-hydroxyarylamine O-acetyltransferase, NAT-2)NAT-2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NAT-2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
NAT-2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to NAT-2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 33 kDa
Purified recombinant protein of human NAT-2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NAT-2 catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates. Participates in the detoxification of a plethora of hydrazine and arylamine drugs, and is able to bioactivate several known carcinogens[1][2].
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
NAT-2 has an amino acid length of 290, molecular weight is 33571 Da.NAT-2 的氨基酸个数为 290 个，分子量为 33571 Da。
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SwissProt ID
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Synonyms
Aac2, Nat2, Arylamine N-acetyltransferase 2, Arylamide acetylase 2, N-acetyltransferase type 2, N-hydroxyarylamine O-acetyltransferase, NAT-2
Documentation
[1]. Zhu Y, et al. Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2. Biol Chem. 2002 Jun;383(6):983-7. [Content Brief]
[2]. Ferguson RJ, et al. Cloning, expression, and functional characterization of two mutant (NAT2(191) and NAT2(341/803)) and wild-type human polymorphic N-acetyltransferase (NAT2) alleles. Drug Metab Dispos. 1994 May-Jun;22(3):371-6. [Content Brief]
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