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Nav Pan Antibody

(Synonyms: SCN1A; SCN2A; SCN3A; SCN4A; SCN5A; SCN8A; SCN9A; SCN10A; SCN11A)

Nav pan Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Nav pan.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Nav Pan Antibody Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
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Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1000 1:200-500 1:3000-5000

Product Details

Description

Nav pan Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Nav pan.

  • Host Rabbit
  • Clonality Polyclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 230 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 227 kDa
Immunogen

Synthetic peptide of human Nav1.1 (center region).

Sensitivity

Endogenous

Purification

Affinity purified

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change (Voltage-gated, voltage-sensitive, or voltage-dependent sodium channel also called VGSCs or Nav channel) or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials. Voltage-gated Na+ channels can exist in any of three distinct states: deactivated (closed), activated (open), or inactivated (closed). Ligand-gated sodium channels are activated by binding of a ligand instead of a change in membrane potential.

  • SwissProt ID

    P35498; Q99250; Q9NY46; P35499; Q14524; Q9UQD0; Q15858; Q9Y5Y9; Q9UI33;

  • Synonyms

    SCN1A; SCN2A; SCN3A; SCN4A; SCN5A; SCN8A; SCN9A; SCN10A; SCN11A

Nav Pan Antibody Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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