NEU1 Antibody (YA7826)
(Synonyms: NANH; NEU; SIAL1)NEU1 Antibody (YA7826) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NEU1.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
NEU1 Antibody (YA7826) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NEU1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 40.2 kDa
Human recombinant protein fragment corresponding to amino acids 48-315 of human NEU1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NEU1 catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage
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Subcellular Localization
Lysosome membrane,Lysosome lumen,Cell membrane,Cytoplasmic vesicle,Lysosome
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Expression
Tissue_Specificity: Highly expressed in pancreas, followed by skeletal muscle, kidney, placenta, heart, lung and liver. Weakly expressed in brain -
Isoforms & Post-Translational Modification
Q99519: 415 amino acids, molecular weight 45467 Da.
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Subunit
Interacts with cathepsin A (protective protein), beta-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex
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SwissProt ID
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Synonyms
NANH; NEU; SIAL1
Documentation
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