NR2C1 Antibody (YA8696)

Cat. No.: HY-P89012: Data Sheet User Guide for Antibodies
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NR2C1 Antibody (YA8696) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NR2C1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

NR2C1 Antibody (YA8696) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NR2C1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 51 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P13056

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-237 of human NR2C1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation

Subcellular Localization：Nucleus,Nucleus, PML body

Isoforms & Post-Translational Modification：P13056 has three isomers: P13056-1: 67315 Da (predicted); P13056-2: 51193 Da (predicted); P13056-3: 53042 Da (predicted).
Sumoylation requires both PIAS1 and UBE2I丨Phosphorylated on several serine and threonine residues

Subunit：Homodimer (By similarity)

Synonyms

TR2

Documentation

User Guide for Antibodies (1077 KB)