NSUN5 Antibody (YA6685)
(Synonyms: FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; p120 antibody; Putative methyltransferase NSUN5 antibody; WBSCR20 antibody; WBSCR20A antibody; Williams Beuren syndrome chromosome region 20A antibody; Williams-Beuren syndrome chromosomal region 20A protein antibody; Williams-Beuren syndrome critical region protein 20 copy A antibody; )NSUN5 Antibody (YA6685) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NSUN5.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:2000 |
Product Details
NSUN5 Antibody (YA6685) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NSUN5.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 47 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 47 kDa
Synthetic peptide within human NSUN5 aa 51-100 / 429.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NSUN5 is a S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development[1][2][3].
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Subcellular Localization
Nucleus, nucleolus
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Expression
Tissue_Specificity: Ubiquitous (PubMed:11978965, PubMed:12073013). Detected in placenta, heart and skeletal muscle (PubMed:11978965, PubMed:12073013)
Induction: Down-regulated in some glioma; epigenetic inactivation is a hallmark of glioma patients with long-term survival -
Isoforms & Post-Translational Modification
Q96P11 has 5 isomers: Q96P11-1: 46692 Da (predicted); Q96P11-2: 50411 Da (predicted); Q96P11-3: 36075 Da (predicted); Q96P11-4: 51061 Da (predicted); Q96P11-5: 42478 Da (predicted).
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SwissProt ID
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Synonyms
FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; FLJ10267 antibody; MGC986 antibody; NOL1 antibody; NOL1-related protein antibody; NOL1/NOP2/Sun domain family member 5 antibody; NOL1R antibody; NOP2/Sun domain family, member 5 antibody; NOP2/Sun domain family, member 5A antibody; NSUN5 antibody; NSUN5_HUMAN antibody; p120 antibody; Putative methyltransferase NSUN5 antibody; WBSCR20 antibody; WBSCR20A antibody; Williams Beuren syndrome chromosome region 20A antibody; Williams-Beuren syndrome chromosomal region 20A protein antibody; Williams-Beuren syndrome critical region protein 20 copy A antibody;
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