ORP1 Antibody (YA1477)(PBS only)

Cat. No.: HY-P81732A: Data Sheet User Guide for Antibodies
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ORP1 Antibody (YA1477) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ORP1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ORP1 Antibody (YA1477) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ORP1.

Host

Rabbit

Molecular Weight

Predicted band size: 108 kDa;

Observed band size: 109,50 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BXW6

Gene ID

114876 [NCBI]

Immunogen

A synthetic peptide of human ORP1 aa937-950.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:200
FC FC: Flow Cytometry	1:10-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193)

Subcellular Localization：Late endosome

Isoforms & Post-Translational Modification：Q9BXW6 has 3 isomers: Q9BXW6-1: 108470 Da (predicted); Q9BXW6-2: 50253 Da (predicted); Q9BXW6-4: 65095 Da (predicted).

Subunit：Interacts (via FFAT motif) with VAPA and VAPB (PubMed:33124732). Interacts with the GTP-bound form of RAB7A (PubMed:17081983).

Research Field

Signal Transduction

Synonyms

ORP1; OSBP8; OSBPL1; OSBPL1B

Documentation

User Guide for Antibodies (1077 KB)