p150 CAF1 Antibody (YA1488)

Cat. No.: HY-P81743: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

p150 CAF1 Antibody (YA1488) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p150 CAF1.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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p150 CAF1 Antibody (YA1488) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

p150 CAF1 Antibody (YA1488) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p150 CAF1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 107 kDa;

Observed band size: 150 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q13111

Gene ID

10036 [NCBI]

Immunogen

A synthetic peptide of human p150 CAF1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:20-1:50
FC FC: Flow Cytometry	1:20-1:50

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：Q13111 has 3 isomers: Q13111-1: 106910 Da (predicted); Q13111-2: 84685 Da (predicted); Q13111-3: 88269 Da (predicted).

Subunit：Homodimer. Part of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. CHAF1A binds directly to CHAF1B. Only minor amounts of RBBP4 are complexed with CHAF1A and CHAF1B in G1 phase. Interacts with PCNA; the interaction is direct (PubMed:10052459, PubMed:10648606). Interacts (via the PxVxL motif) with CBX5; the interaction is direct (PubMed:15882967, PubMed:20562864). Interacts with MBD1 (PubMed:12697822). Interacts with histones H3.1, H3.2 and H3.1t (PubMed:33857403)

Database

Entrez Gene: 10036 Human

SwissProt: Q13111 Human

OMIM: 601246 Human

Research Field

Epigenetics and Nuclear Signaling

Synonyms

CHAF1A; CAF; CAF1P150; Chromatin assembly factor 1 subunit A; CAF-1 subunit A; Chromatin assembly factor I p150 subunit; CAF-I 150 kDa subunit; CAF-I p150; hp150

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

p150 CAF1 Antibody (YA1488) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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p150 CAF1 Antibody (YA1488)

p150 CAF1 Antibody (YA1488) Featured Recommendations:

Product Detail

Background

Documentation

p150 CAF1 Antibody (YA1488) Related Classifications

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