2. Gene
  3. CHAF1A - chromatin assembly factor 1 subunit A Gene

CHAF1A - chromatin assembly factor 1 subunit A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CAF1; P150; CAF-1; CAF1B; CAF1P150

Gene ID: 10036 | Gene type: protein coding

About CHAF1A

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,402,640-4,450,830 (from NCBI)

This gene has 7 transcripts (splice variants) and 200 orthologues. Broad expression in bone marrow (RPKM 7.4), testis (RPKM 6.1) and 24 other tissues.

Summary

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008]

CHAF1A Products(1)

mRNA Protein Name
NM_005483.3 NP_005474.2 chromatin assembly factor 1 subunit A

CHAF1A Protein Structure

CAF1-p150_N

CAF1-p150_N: CAF1 complex subunit p150, region binding to PCNA (1 - 229)

CAF-1_p150

CAF-1_p150: Chromatin assembly factor 1 complex p150 subunit, N-terminal (267 - 479)

CAF1A

CAF1A: Chromatin assembly factor 1 subunit A (557 - 634)

CAF1-p150_C2

CAF1-p150_C2: CAF1 complex subunit p150, region binding to CAF1-p60 at C-term (665 - 956)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 956 a.a.
Protein Preferred Names Protein Names

chromatin assembly factor 1 subunit A

CAF-1 subunit A

Related Diseases

Diseases Alias
Prostate Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Prostate
Digeorge Syndrome

Chromosome 22q11.2 Deletion Syndrome

DGS

Hypoplasia Of Thymus And Parathyroids

Third And Fourth Pharyngeal Pouch Syndrome

22q11.2 Deletion Syndrome

Digeorge Sequence

Digeorge'S Syndrome

Pharyngeal Pouch Syndrome

Di-George Syndrome

Shprintzen Syndrome
Alpha Thalassemia-Intellectual Disability Syndrome Type 1

Alpha Thalassemia-Intellectual Disability Syndrome, Deletion Type

Alpha-Thalassemia-Intellectual Disability Syndrome Linked To Chromosome 16

Atr Syndrome Linked To Chromosome 16

Atr Syndrome, Deletion Type

Atr-16 Syndrome

Alpha Thalassemia-Retardation Syndrome

Alpha-Thalassemia/Mental Retardation Syndrome, Deletion-Type

Alpha-Thalassemia/Mental Retardation Syndrome, Type 1

Alpha-Thalassemia Mental Retardation Syndrome, Deletion-Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02594 CHAF1A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CHAF1A RGD RGD:1590865
Canis familiaris CHAF1A VGNC VGNC:39189
Bos taurus CHAF1A VGNC VGNC:27266
Felis catus CHAF1A VGNC VGNC:60835
Macaca mulatta CHAF1A VGNC VGNC:71024
Mus musculus CHAF1A MGD MGI:1351331