Palladin Antibody (YA6711)

Cat. No.: HY-P87018: Data Sheet User Guide for Antibodies
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Palladin Antibody (YA6711) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Palladin.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Palladin Antibody (YA6711) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Palladin.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 151 kDa;

Observed band size: 110/151 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8WX93

Gene ID

23022 [NCBI]

Immunogen

Recombinant protein within Human Palladin aa 1-100 / 1,383.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci

Subcellular Localization：Cytoplasm, cytoskeleton,Cell junction, focal adhesion,Cytoplasm, myofibril, sarcomere, Z line,Cell projection, ruffle,Cell projection, podosome,Cell projection, lamellipodium,Cell projection, axon,Cell projection, growth cone

Expression：
Tissue_Specificity: Detected in both muscle and non-muscle tissues. High expression in prostate, ovary, colon, and kidney. Not detected in spleen, skeletal muscle, lung and peripheral blood lymphocytes (at protein level). Protein is overexpressed in FA6, HPAF, IMIM-PC2, SUIT-2 and PancTu-II sporadic pancreatic cancer cell lines
Induction: Isoform 3 is expressed de novo. Isoform 4 is up-regulated by TGFB1 during myofibroblast differentiation

Isoforms & Post-Translational Modification：Q8WX93 has 9 isomers: Q8WX93-1: 150564 Da (predicted); Q8WX93-2: 122047 Da (predicted); Q8WX93-3: 108632 Da (predicted); Q8WX93-4: 73322 Da (predicted); Q8WX93-5: 127826 Da (predicted); Q8WX93-6: 58796 Da (predicted); Q8WX93-7: 42933 Da (predicted); Q8WX93-8: 85894 Da (predicted); Q8WX93-9: 123693 Da (predicted).
Phosphorylated predominantly on serines and, to a lesser extent, on tyrosines (By similarity)

Subunit：Interacts with EPS8 (By similarity)

Synonyms

CGI 151 antibody; CGI151 antibody; KIAA0992 antibody; MYN antibody; Myoneurin antibody; pa antibody; Palladin cytoskeletal associated protein antibody; Palld antibody; PNCA1 antibody; Sarcoma antigen NY SAR 77 antibody; CGI 151 antibody; CGI151 antibody; KIAA0992 antibody; MYN antibody; Myoneurin antibody; pa antibody; Palladin cytoskeletal associated protein antibody; Palld antibody; PNCA1 antibody; Sarcoma antigen NY SAR 77 antibody; SIH002 antibody; Stx13bp1 antibody;

각종 서류

User Guide for Antibodies (1077 KB)