Palladin Antibody (YA6711)
(Synonyms: CGI 151 antibody; CGI151 antibody; KIAA0992 antibody; MYN antibody; Myoneurin antibody; pa antibody; Palladin cytoskeletal associated protein antibody; Palld antibody; PNCA1 antibody; Sarcoma antigen NY SAR 77 antibody; CGI 151 antibody; CGI151 antibody; KIAA0992 antibody; MYN antibody; Myoneurin antibody; pa antibody; Palladin cytoskeletal associated protein antibody; Palld antibody; PNCA1 antibody; Sarcoma antigen NY SAR 77 antibody; SIH002 antibody; Stx13bp1 antibody; )Palladin Antibody (YA6711) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Palladin.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB
-
Reactivity :
Human
-
Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000 |
Product Details
Palladin Antibody (YA6711) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Palladin.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 110/151 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 151 kDa
Recombinant protein within Human Palladin aa 1-100 / 1,383.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Palladin is a Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci
-
Subcellular Localization
Cytoplasm, cytoskeleton,Cell junction, focal adhesion,Cytoplasm, myofibril, sarcomere, Z line,Cell projection, ruffle,Cell projection, podosome,Cell projection, lamellipodium,Cell projection, axon,Cell projection, growth cone
-
Expression
Tissue_Specificity: Detected in both muscle and non-muscle tissues. High expression in prostate, ovary, colon, and kidney. Not detected in spleen, skeletal muscle, lung and peripheral blood lymphocytes (at protein level). Protein is overexpressed in FA6, HPAF, IMIM-PC2, SUIT-2 and PancTu-II sporadic pancreatic cancer cell lines
Induction: Isoform 3 is expressed de novo. Isoform 4 is up-regulated by TGFB1 during myofibroblast differentiation -
Isoforms & Post-Translational Modification
Q8WX93 has 9 isomers: Q8WX93-1: 150564 Da (predicted); Q8WX93-2: 122047 Da (predicted); Q8WX93-3: 108632 Da (predicted); Q8WX93-4: 73322 Da (predicted); Q8WX93-5: 127826 Da (predicted); Q8WX93-6: 58796 Da (predicted); Q8WX93-7: 42933 Da (predicted); Q8WX93-8: 85894 Da (predicted); Q8WX93-9: 123693 Da (predicted).
Phosphorylated predominantly on serines and, to a lesser extent, on tyrosines (By similarity) -
Subunit
Interacts with EPS8 (By similarity)
-
SwissProt ID
-
Synonyms
CGI 151 antibody; CGI151 antibody; KIAA0992 antibody; MYN antibody; Myoneurin antibody; pa antibody; Palladin cytoskeletal associated protein antibody; Palld antibody; PNCA1 antibody; Sarcoma antigen NY SAR 77 antibody; CGI 151 antibody; CGI151 antibody; KIAA0992 antibody; MYN antibody; Myoneurin antibody; pa antibody; Palladin cytoskeletal associated protein antibody; Palld antibody; PNCA1 antibody; Sarcoma antigen NY SAR 77 antibody; SIH002 antibody; Stx13bp1 antibody;
Documentation
Powered by Bioz
