PE-CF596-conjugated IFN-γ Antibody (4S.B3)
(Synonyms: IFN-γ,IFN-γ-PE-CF596,4S.B3)PE-CF596-conjugated IFN-γ Antibody (4S.B3) is a Mouse-derived and PE-CF596 conjugated monoclonal antibody, targeting to IFN-γ.
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Host:
Mouse
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Isotype:
Mouse IgG1,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
PE-CF596
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
IFN-γ (Interferon-gamma) is a key immune cytokine produced by NK cells, Th1 cells, and CD8⁺ T cells. It regulates macrophage activation, Th1 differentiation, antigen presentation, and anti-tumor immunity via the IFNGR-JAK-STAT1 pathway. IFN-γ serves as an important indicator for assessing cellular immune function, T-cell activation status, and the efficacy of immunotherapy.
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:Mainly released by activated T lymphocytes
Induction:By cytokines, most notably interleukin IL-12, secreted by professional antigen-presenting cells such as monocytes/macrophages and dendritic cells -
Subunit
Homodimer. Interacts with IFNGR1 (via extracellular domain); this interaction promotes IFNGR1 dimerization
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Synonyms
IFN-γ,IFN-γ-PE-CF596,4S.B3
Documentation
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