PE-conjugated CD64 Antibody (10.1)
(Synonyms: CD64,CD64-PE,10.1)PE-conjugated CD64 Antibody (10.1) is a Mouse-derived and PE conjugated monoclonal antibody, targeting to CD64.
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Host:
Mouse
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Isotype:
Mouse IgG1,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
PE
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
PE-conjugated CD64 Antibody (10.1) is a Mouse-derived and PE conjugated monoclonal antibody, targeting to CD64.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
PE
Unmodified
Mouse IgG1,κ
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
FcγRI (CD64) is a high-affinity receptor for the Fc region of immunoglobulin γ. FcγRI (CD64) is constitutively expressed by monocytes, macrophages, and many myeloid progenitor cells. FcγRI (CD64) plays a role in both innate and adaptive immune responses. FcγRI (CD64) mediates the effector function of IgG on monocytes, thereby triggering antibody-dependent cytotoxicity (ADCC) to kill virus-infected cells.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Monocyte/macrophage specific -
Isoforms & Post-Translational Modification
CD64 has 2 isomers: P12314-1: 42632 Da (predicted); P12314-2: 38795 Da (predicted).
Phosphorylated on serine residues -
Subunit
Interacts with IGHG1. Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL. Interacts with HCK and LYN
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Synonyms
CD64,CD64-PE,10.1
Documentation
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