Peripherin Antibody (YA5388)

Cat. No.: HY-P85696: Data Sheet User Guide for Antibodies
FAQs
Technical Support

Peripherin Antibody (YA5388) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Peripherin.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

Peripherin Antibody (YA5388) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Peripherin.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Observed band size: 55 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

P41219

Gene ID

5630 [NCBI]

Immunogen

Synthesized peptide derived from human Peripherin

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-2000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Solution

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Class-III neuronal intermediate filament protein (By similarity). May form an independent structural network without the involvement of other neurofilaments or may cooperate with the neuronal intermediate filament proteins NEFL, NEFH, NEFM and INA to form a filamentous network (PubMed:15322088, PubMed:15446584). Assembly of the neuronal intermediate filaments may be regulated by RAB7A (By similarity). Plays a role in the development of unmyelinated sensory neurons (By similarity). May be involved in axon elongation and axon regeneration after injury (By similarity). Inhibits neurite extension in type II spiral ganglion neurons in the cochlea (By similarity)

Subcellular Localization：Cytoplasm, cytoskeleton; Cell projection, axon; Perikaryon

Expression：
Tissue_specificity:Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells

Isoforms & Post-Translational Modification：P41219 has 2 isomers: P41219-1: 53651 Da (predicted); P41219-2: 53779 Da (predicted).
Phosphorylated; phosphorylation increases after nerve injury in regenerating neurons

Subunit：Forms homodimers (in vitro) (By similarity). Homopolymerizes into a filamentous network (in vitro) (PubMed:15446584). Forms heterodimers with NEFL, NEFM or NEFH (in vitro) (By similarity). Interacts with DST (via C-terminus) (By similarity). Interacts with RAB7A; the interaction is direct (PubMed:23179371). Interacts with PRKCE (via phorbol-ester/DAG-type 2 domain) (PubMed:18408015)

Synonyms

Peripherin; Neurofilament 4;

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/panc-1-cell.html [Content Brief]