Phospho-CRMP2 (Thr514) Antibody (YA9812)
(Synonyms: DRP2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2; DPYSL2; CRMP2; ULIP2; Musunc33; TOAD64)
Based on 1 Customer Validation
Phospho-CRMP2 (Thr514) Antibody (YA9812) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-CRMP2 (Thr514).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000 |
Product Details
Phospho-CRMP2 (Thr514) Antibody (YA9812) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-CRMP2 (Thr514).
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 62 kDa
Synthetic peptide surrounding Thr514 of human CRMP-2.
Endogenous
affinity purified
Non-conjugated
Phosphorylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CRMP2 plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis
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Subcellular Localization
Cytoplasm, cytosol; Cytoplasm, cytoskeleton; Membrane
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Expression
Tissue_Specificity: Ubiquitous. -
Isoforms & Post-Translational Modification
Phospho-CRMP2 has 2 isoforms, Q16555-1: amino acid length is 572, molecular weight is 62294 Da (predicted); Q16555-2: amino acid length is 536, molecular weight is 58163 Da (predicted).
3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509. -
Subunit
Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5.
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SwissProt ID
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Synonyms
DRP2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2; DPYSL2; CRMP2; ULIP2; Musunc33; TOAD64
Documentation
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