Phospho-MAP2 (Ser136) Antibody (YA9877)
(Synonyms: DKFZp686I2148; MAP 2; MAP dendrite specific; MAP-2; MAP2; MAP2A; MAP2B; MAP2C; Microtubule associated protein 2; Microtubule-associated protein 2)
Based on 1 Customer Validation
Phospho-MAP2 (Ser136) Antibody (YA9877) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-MAP2 (Ser136).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue
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Reactivity :
Mouse, Rat
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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|---|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:200 | 1:1000 | 1:100 |
Product Details
Phospho-MAP2 (Ser136) Antibody (YA9877) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-MAP2 (Ser136).
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Host Rabbit
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Species ReactivityMouse, Rat
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Observed Molecular WeightObserved band size: 200 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 200 kDa
Synthetic phosphopeptide corresponding to residues surrounding Ser136 of human MAP2.
Endogenous
affinity purified
Non-conjugated
Phosphorylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol, 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MAP2 is a The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules
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Subcellular Localization
Cytoplasm, cytoskeleton; Cell projection, dendrite
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Isoforms & Post-Translational Modification
Phospho-MAP2 has an amino acid length of 1828, molecular weight is 199132 Da.MAP/微管亲和调节激酶(MARK1 或 MARK2)可介导其 K-X-G-S 基序中的丝氨酸残基磷酸化，使其从微管上脱离，导致微管解聚(依据相似性)。与 KNDC1 的相互作用可增强 MAP2 的苏氨酸磷酸化(PubMed:17984326)Phospho-MAP2 的氨基酸个数为 1828 个，分子量为 199132 Da。Phosphorylated at serine residues in K-X-G-S motifs by causing MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), detachment from microtubules, and their disassembly (By similarity). The interaction with KNDC1 enhances MAP2 threonine phosphorylation (PubMed:17984326)
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Subunit
Interacts with KNDC1 (via KIND2); the interaction enhances MAP2 phosphorylation and localizes KNDC1 to dendrites.
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SwissProt ID
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Synonyms
DKFZp686I2148; MAP 2; MAP dendrite specific; MAP-2; MAP2; MAP2A; MAP2B; MAP2C; Microtubule associated protein 2; Microtubule-associated protein 2
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