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Phospho-UBF1 (S484) Antibody (YA6733)

(Synonyms: 90 kDa nucleolus organizer region autoantigen antibody; Autoantigen NOR-90 antibody; NOR 90 antibody; Nucleolar transcription factor 1 antibody; UBF 1 antibody; UBF antibody; UBF-1 antibody; UBF1_HUMAN antibody; Ubtf antibody; Upstream binding factor 1 antibody; 90 kDa nucleolus organizer region autoantigen antibody; Autoantigen NOR-90 antibody; NOR 90 antibody; Nucleolar transcription factor 1 antibody; UBF 1 antibody; UBF antibody; UBF-1 antibody; UBF1_HUMAN antibody; Ubtf antibody; Upstream binding factor 1 antibody; upstream binding transcription factor, RNA polymerase I antibody; Upstream-binding factor 1 antibody; )
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Phospho-UBF1 (S484) Antibody (YA6733) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-UBF1 (S484).

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • Phospho-UBF1 (S484) Antibody (YA6733) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000 1:1000

Product Details

Description

Phospho-UBF1 (S484) Antibody (YA6733) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-UBF1 (S484).

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 89 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 89 kDa
Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Ser484 of human UBF1.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Phosphorylated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    UBF1 recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I (Pol I) through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element and can activate Pol I promoter escape

  • Subcellular Localization

    Nucleus, nucleolus

  • Isoforms & Post-Translational Modification

    P17480 has two isomers: P17480-1: 89406 Da (predicted); P17480-2: 84937 Da (predicted).
    Phosphorylated and activated by PIK3CA

  • Subunit

    Homodimer (By similarity)

  • SwissProt ID

    P17480

  • Gene ID
    7343 [NCBI]
  • Synonyms

    90 kDa nucleolus organizer region autoantigen antibody; Autoantigen NOR-90 antibody; NOR 90 antibody; Nucleolar transcription factor 1 antibody; UBF 1 antibody; UBF antibody; UBF-1 antibody; UBF1_HUMAN antibody; Ubtf antibody; Upstream binding factor 1 antibody; 90 kDa nucleolus organizer region autoantigen antibody; Autoantigen NOR-90 antibody; NOR 90 antibody; Nucleolar transcription factor 1 antibody; UBF 1 antibody; UBF antibody; UBF-1 antibody; UBF1_HUMAN antibody; Ubtf antibody; Upstream binding factor 1 antibody; upstream binding transcription factor, RNA polymerase I antibody; Upstream-binding factor 1 antibody;

Phospho-UBF1 (S484) Antibody (YA6733) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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