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PMF 1 Antibody (YA3165)(PBS only)

(Synonyms: Polyamine-modulated factor 1)

PMF 1 Antibody (YA3165) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PMF 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IP

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PMF 1 Antibody (YA3165)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:500-1:1000 1:20

Product Details

Description

PMF 1 Antibody (YA3165) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PMF 1.

  • Host Rabbit
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 23 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 23 kDa
Immunogen

Recombinant protein of human PMF-1

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PMF 1 is a Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT

  • Subcellular Localization

    Nucleus; Chromosome, centromere, kinetochore

  • Expression


    Tissue_specificity:Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver

    Induction:By polyamine analogs in analog-sensitive H157 cells

  • Isoforms & Post-Translational Modification

    Q6P1K2 has 6 isomers: Q6P1K2-1: 23339 Da (predicted); Q6P1K2-2: 22946 Da (predicted); Q6P1K2-3: 18977 Da (predicted); Q6P1K2-4: 19238 Da (predicted); Q6P1K2-5: 24032 Da (predicted); Q6P1K2-6: 20230 Da (predicted).

  • Subunit

    Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Interacts with COPS7A. Interacts via its coiled-coil domain with the leucine-zipper domain of NFE2L2. The interaction with NFE2L2 is required for the transcriptional regulation of SSAT

  • SwissProt ID

    Q6P1K2

  • Gene ID
    100527963 [NCBI]
  • Synonyms

    Polyamine-modulated factor 1

  • Research Field

    -

PMF 1 Antibody (YA3165)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PMF 1 Antibody (YA3165)(PBS only) Product Image
    1/16
  • PMF 1 Antibody (YA3165)(PBS only) Product Image