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PPCEL Antibody (YA3175)(PBS only)

(Synonyms: CMS22; Prolylendopeptidase-like)

PPCEL Antibody (YA3175) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPCEL.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IP

  • Reactivity :

    Human, Mouse, Rat, Hamster

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PPCEL Antibody (YA3175)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:500-1:1000 1:50-1:100 1:20

Product Details

Description

PPCEL Antibody (YA3175) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPCEL.

  • Host Rabbit
  • Species Reactivity
    Human, Mouse, Rat, Hamster
  • Observed Molecular Weight
    Observed band size: 72 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 84 kDa
Immunogen

Recombinant protein of human PPCEL/PREPL aa451-651.

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PPCEL serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis[1][2][3][4][5].

  • Subcellular Localization

    Cytoplasm, cytosol; Golgi apparatus, trans-Golgi network; Cytoplasm, cytoskeleton; Golgi apparatus; Nucleus

  • Expression


    Tissue_specificity:Expressed in pyramidal neurons of the temporal cortex and neocortex (at protein level) (PubMed:23485813) . Widely expressed (PubMed:15913950, PubMed:16385448) . Expressed at higher level in brain, skeletal muscle, heart and kidney (PubMed:15913950, PubMed:16385448) . Expressed at the endplates in the neuromuscular junction (PubMed:24610330)

  • Isoforms & Post-Translational Modification

    Q4J6C6 has 4 isomers: Q4J6C6-1: 83927 Da (predicted); Q4J6C6-2: 76352 Da (predicted); Q4J6C6-3: 76757 Da (predicted); Q4J6C6-4: 73352 Da (predicted).

  • Subunit

    Homodimer (PubMed:16143824). Interacts with the AP-1 complex (PubMed:23321636)

  • SwissProt ID

    Q4J6C6

  • Gene ID
    9581 [NCBI]
  • Synonyms

    CMS22; Prolylendopeptidase-like

  • Research Field

    -

PPCEL Antibody (YA3175)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • PPCEL Antibody (YA3175)(PBS only) Product Image