PPP2R5D Antibody (YA1705)
(Synonyms: B56D; MRD35; B56delta)PPP2R5D Antibody (YA1705) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPP2R5D.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:20 |
Product Details
PPP2R5D Antibody (YA1705) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPP2R5D.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 70,66 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 70 kDa
Recombinant protein of human PPP2R5D
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PPP2R5D is a The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_specificity:Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain
Induction:By retinoic acid; in neuroblastoma cell lines -
Isoforms & Post-Translational Modification
Q14738 has 3 isomers: Q14738-1: 69992 Da (predicted); Q14738-2: 66181 Da (predicted); Q14738-3: 58453 Da (predicted).
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Subunit
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with the PP2A A subunit PPP2R1A (PubMed:37761890). Interacts with SGO1 (PubMed:16541025). Interacts with ADCY8 (PubMed:22976297)
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SwissProt ID
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Synonyms
B56D; MRD35; B56delta
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Research Field
Neuroscience
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