PPP2R5D Antibody (YA1705)

製品番号: HY-P81960: データシート User Guide for Antibodies
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PPP2R5D Antibody (YA1705) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPP2R5D.

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容量	価格（税別）	在庫状況	数量
20 μL	$146	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	$222	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	$360	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

Synthetic products have potential research and development risk.

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* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

PPP2R5D Antibody (YA1705) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPP2R5D.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 70 kDa;

Observed band size: 70,66 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q14738

Gene ID

5528 [NCBI]

Immunogen

Recombinant protein of human PPP2R5D

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:20

Sensitivity	Endogenous	純度	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment

Subcellular Localization：Cytoplasm; Nucleus

Expression：
Tissue_specificity:Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain

Induction:By retinoic acid; in neuroblastoma cell lines

Isoforms & Post-Translational Modification：Q14738 has 3 isomers: Q14738-1: 69992 Da (predicted); Q14738-2: 66181 Da (predicted); Q14738-3: 58453 Da (predicted).

Subunit：PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with the PP2A A subunit PPP2R1A (PubMed:37761890). Interacts with SGO1 (PubMed:16541025). Interacts with ADCY8 (PubMed:22976297)

Database

Entrez Gene: 5528 Human ; 21770 Mouse ; 363193 Rat

SwissProt: Q14738 Human ;

OMIM: 616355 Human

Research Field

Neuroscience

Synonyms

B56D; MRD35; B56delta

ドキュメンテーション

User Guide for Antibodies (1077 KB)