PYCR1 Antibody (YA8832)(PBS only)
(Synonyms: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR)PYCR1 Antibody (YA8832) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYCR1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
PYCR1 Antibody (YA8832) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYCR1.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 33.2 kDa
Human recombinant protein fragment corresponding to amino acids 1-319 of human PYCR1 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PYCR1 is an Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress[1][2][3][4].
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Subcellular Localization
Mitochondrion
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Isoforms & Post-Translational Modification
P32322 has three isomers: P32322-1: 33361 Da (predicted); P32322-2: 33341 Da (predicted); P32322-3: 35981 Da (predicted).
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Subunit
Homodecamer; composed of 5 homodimers (PubMed:16730026, PubMed:28258219, Ref
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SwissProt ID
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Synonyms
ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR
Documentation