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  5. PYCR1 Antibody (YA8832)(PBS only)

PYCR1 Antibody (YA8832)(PBS only)

Cat. No.: HY-P89148A
User Guide for Antibodies Technical Support

PYCR1 Antibody (YA8832) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYCR1.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

PYCR1 Antibody (YA8832) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYCR1.
Host

Mouse
Molecular Weight

Predicted band size: 33.2 kDa
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Human recombinant protein fragment corresponding to amino acids 1-319 of human PYCR1 produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:500-800
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H (PubMed:16730026, PubMed:19648921, PubMed:23024808, PubMed:28258219). At physiologic concentrations, has higher specific activity in the presence of NADH (PubMed:16730026, PubMed:23024808). Involved in the cellular response to oxidative stress (PubMed:16730026, PubMed:19648921)
Subcellular Localization：Mitochondrion
Isoforms & Post-Translational Modification：P32322 has three isomers: P32322-1: 33361 Da (predicted); P32322-2: 33341 Da (predicted); P32322-3: 35981 Da (predicted).
Subunit：Homodecamer; composed of 5 homodimers (PubMed:16730026, PubMed:28258219, Ref
Synonyms
ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR
Documentation
User Guide for Antibodies (1077 KB)

PYCR1 Antibody (YA8832)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PYCR1 Antibody (YA8832)(PBS only)
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