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RAGE Antibody (YA8402)

(Synonyms: RAGE; RAGE-1; RAGE1; STK30)

RAGE Antibody (YA8402) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAGE.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

RAGE Antibody (YA8402) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAGE.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 47.8 kDa
Immunogen

Human recombinant protein fragment corresponding to amino acids 205-419 of human RAGE produced in E.coli.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner

  • Subcellular Localization

    Cytoplasm,Cell projection, cilium,Nucleus

  • Expression


    Tissue_Specificity: Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina

  • Isoforms & Post-Translational Modification

    Q9UQ07 has 6 isomers: Q9UQ07-1: 48014 Da (predicted); Q9UQ07-2: 27120 Da (predicted); Q9UQ07-3: 7879 Da (predicted); Q9UQ07-4: 10482 Da (predicted); Q9UQ07-5: 44425 Da (predicted); Q9UQ07-6: 47886 Da (predicted).
    Autophosphorylated

  • SwissProt ID

    Q9UQ07

  • Synonyms

    RAGE; RAGE-1; RAGE1; STK30

RAGE Antibody (YA8402) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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