2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. RGS17 Antibody (YA7938)

RGS17 Antibody (YA7938) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RGS17.

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容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

RGS17 Antibody (YA7938) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RGS17.
Host

Mouse
Clonality

Monoclonal
分子量

Predicted band size: 24.2 kDa
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Full length human recombiant protein of human RGS17 produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:500-800
Sensitivity Endogenous 純度 Affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity)
Subcellular Localization：Membrane,Synapse, synaptosome,Nucleus,Cytoplasm
Expression：
Tissue_Specificity: Predominantly expressed in the cerebellum. Also expressed in the cortex and medulla. Weakly expressed in a number of peripheral tissues notably spleen, lung and leukocytes
Isoforms & Post-Translational Modification：Q9UGC6: 210 amino acids, molecular weight 24359 Da.
Subunit：Interacts with GNAI1 and GNAQ (PubMed:18434541)
Synonyms
hRGS17; RGS-17; RGSZ2
ドキュメンテーション
User Guide for Antibodies (1077 KB)

RGS17 Antibody (YA7938) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
RGS17 Antibody (YA7938)
製品番号:
HY-P88254
数量:
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