RGS6 Antibody (YA3211)(PBS only)

Art. -Nr.: HY-P83466A: Data Sheet User Guide for Antibodies
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RGS6 Antibody (YA3211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RGS6.

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100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung
Verweise

Beschreibung

RGS6 Antibody (YA3211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RGS6.

Host

Rabbit

Molekulargewicht

Predicted band size: 54 kDa;

Observed band size: 54 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P49758

Gene ID

9628 [NCBI]

Immunogen

A synthetic peptide of human RGS6 aa443-455.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Reinheit	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509)

Subcellular Localization：Cytoplasm; Cytoplasm, cytosol; Membrane; Peripheral membrane protein; Nucleus; Cell membrane

Isoforms & Post-Translational Modification：P49758 has 15 isomers: P49758-4: 54423 Da (predicted); P49758-2: 56138 Da (predicted); P49758-3: 56512 Da (predicted); P49758-5: 53787 Da (predicted); P49758-6: 49520 Da (predicted); P49758-7: 50155 Da (predicted); P49758-8: 54049 Da (predicted); P49758-9: 52245 Da (predicted); P49758-10: 51870 Da (predicted); P49758-11: 49781 Da (predicted); P49758-12: 40588 Da (predicted); P49758-13: 54953 Da (predicted); P49758-14: 55270 Da (predicted); P49758-15: 55614 Da (predicted); P49758-16: 53319 Da (predicted).

Subunit：Interacts with GNB5 (PubMed:10339615, PubMed:10521509, PubMed:12761221). Interacts with GNAI1 (PubMed:18434541)

Research Field

Synonyms

regulator of G protein signaling 6; GAP; S914; HA117

Dokumentation

User Guide for Antibodies (1077 KB)

Verweise

[1]. /biology-dictionary/cho-cell.html [Content Brief]