RGS6 Antibody (YA7518)

Cat. No.: HY-P87833: Data Sheet User Guide for Antibodies
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RGS6 Antibody (YA7518) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to RGS6.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

RGS6 Antibody (YA7518) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to RGS6.

Host

Rabbit

Clonality

Monoclonal,Recombinant

Molecular Weight

Predicted band size: 52 kDa;

Observed band size: 52 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P49758

Immunogen

The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000

Sensitivity	Endogenous	Purity	Protein A affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG, Kappa

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509)

Subcellular Localization：Cytoplasm,Cytoplasm, cytosol,Membrane,Nucleus,Cell membrane

Isoforms & Post-Translational Modification：P49758 has 15 isomers: P49758-4: 54423 Da (predicted); P49758-2: 56138 Da (predicted); P49758-3: 56512 Da (predicted); P49758-5: 53787 Da (predicted); P49758-6: 49520 Da (predicted); P49758-7: 50155 Da (predicted); P49758-8: 54049 Da (predicted); P49758-9: 52245 Da (predicted); P49758-10: 51870 Da (predicted); P49758-11: 49781 Da (predicted); P49758-12: 40588 Da (predicted). P49758-13: 54953 Da (predicted); P49758-14: 55270 Da (predicted); P49758-15: 55614 Da (predicted); P49758-16: 53319 Da (predicted).

Subunit：Interacts with GNB5 (PubMed:10339615, PubMed:10521509, PubMed:12761221)

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/mda-mb-231-cell.html [Content Brief]