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Cat. No.: HY-P87833

RGS6 Antibody (YA7518)

RGS6 Antibody (YA7518) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to RGS6.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Price

Stock

Quantity

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot
Dilution Ratio	1:1000-1:5000

Description

RGS6 Antibody (YA7518) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to RGS6.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 52 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 52 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG, Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

RGS6 regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity^[1].
Subcellular Localization

Cytoplasm,Cytoplasm, cytosol,Membrane,Nucleus,Cell membrane
Isoforms & Post-Translational Modification

P49758 has 15 isomers: P49758-4: 54423 Da (predicted); P49758-2: 56138 Da (predicted); P49758-3: 56512 Da (predicted); P49758-5: 53787 Da (predicted); P49758-6: 49520 Da (predicted); P49758-7: 50155 Da (predicted); P49758-8: 54049 Da (predicted); P49758-9: 52245 Da (predicted); P49758-10: 51870 Da (predicted); P49758-11: 49781 Da (predicted); P49758-12: 40588 Da (predicted). P49758-13: 54953 Da (predicted); P49758-14: 55270 Da (predicted); P49758-15: 55614 Da (predicted); P49758-16: 53319 Da (predicted).
Subunit

Interacts with GNB5 (PubMed:10339615, PubMed:10521509, PubMed:12761221)
SwissProt ID

P49758