Copy Link Print Information

SAMSN1 Antibody (YA8758)(PBS only)

(Synonyms: HACS1; NASH1; SASH2; SH3D6B; SLy2)

SAMSN1 Antibody (YA8758) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SAMSN1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • SAMSN1 Antibody (YA8758)(PBS only) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

SAMSN1 Antibody (YA8758) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SAMSN1.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 41.5 kDa
Immunogen

Human recombinant protein fragment corresponding to amino acids 1-250 of human SAMSN1 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SAMSN1 is a Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation

  • Subcellular Localization

    Nucleus,Cytoplasm,Cell projection, ruffle

  • Expression


    Tissue_Specificity: Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood
    Induction: Up-regulated in peripheral blood B-cells by IL4, IL13 and by CD40 stimulation

  • Isoforms & Post-Translational Modification

    Q9NSI8 has three isomers: Q9NSI8-1: 41708 Da (predicted); Q9NSI8-2: 23466 Da (predicted); Q9NSI8-3: 49627 Da (predicted).

  • Subunit

    Interacts with FASLG

  • SwissProt ID

    Q9NSI8

  • Synonyms

    HACS1; NASH1; SASH2; SH3D6B; SLy2

SAMSN1 Antibody (YA8758)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • SAMSN1 Antibody (YA8758)(PBS only) Product Image
    1/16
  • SAMSN1 Antibody (YA8758)(PBS only) Product Image