SLC39A5 Antibody (YA8179)(PBS only)

Art. -Nr.: HY-P88495A: Data Sheet User Guide for Antibodies
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SLC39A5 Antibody (YA8179) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC39A5.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Größe		Verfügbarkeit
50 μL		Angebot einholen
100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

SLC39A5 Antibody (YA8179) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC39A5.

Host

Mouse

Molekulargewicht

Predicted band size: 56.1 kDa

Species Reactivity

Human

SwissProt ID

Q6ZMH5

Immunogen

Human recombinant protein fragment corresponding to amino acids 48-178 of human SLC39A5 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Reinheit	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Uniporter that transports zinc(2+) into polarized cells of enterocytes, pancreatic acinar and endoderm cells across the basolateral membrane and participates, notably, in zinc excretion from the intestine by the uptake of zinc from the blood into the intestine (By similarity). The transport mechanism is temperature- and concentration-dependent and saturable (By similarity). In addition, is also a high affinity copper transporter in vitro (PubMed:36454509). Also may regulate glucose-stimulated insulin secretion (GSIS) in islets primarily through the zinc-activated SIRT1-PPARGC1A axis (By similarity). Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Plays a role in eye development (PubMed:24891338)

Subcellular Localization：Basolateral cell membrane

Expression：
Tissue_Specificity: Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney

Isoforms & Post-Translational Modification：Q6ZMH5: 540 amino acids, molecular weight 56461 Da.

Subunit：Homodimer

Synonyms

LZT-Hs7; MYP24; ZIP5

Dokumentation

User Guide for Antibodies (1077 KB)