SMG5 Antibody
(Synonyms: Protein SMG5, EST1-like protein B, LPTS-RP1, LPTS-interacting protein, SMG-5 homolog, hSMG-5, SMG5, EST1B, KIAA1089, EST1 like protein B)
Based on 1 Customer Validation
SMG5 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to SMG5.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-5000 |
Product Details
SMG5 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to SMG5.
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Host Rabbit
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Clonality polyclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 114 kDa;
Recombinant protein of human SMG5 aa 800-1000.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SMG5 plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_Specificity: Ubiquitous. -
Isoforms & Post-Translational Modification
SMG5 has an amino acid length of 1016, molecular weight is 113928 Da.
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Subunit
Interacts with TERT, PPP2CA and SMG1.
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SwissProt ID
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Synonyms
Protein SMG5, EST1-like protein B, LPTS-RP1, LPTS-interacting protein, SMG-5 homolog, hSMG-5, SMG5, EST1B, KIAA1089, EST1 like protein B
Documentation
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