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Steroid sulfatase Antibody (YA6938)

(Synonyms: ARSC antibody)

Steroid sulfatase Antibody (YA6938) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Steroid sulfatase.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • Steroid sulfatase Antibody (YA6938) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:2000 1:3000

Product Details

Description

Steroid sulfatase Antibody (YA6938) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Steroid sulfatase.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 65 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size：65 kDa
Immunogen

Recombinant protein within Human Steroid sulfatase aa 22-184 and aa 235-583.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Steroid sulfatase (STS) is a glycosylated protein with an apparent molecular weight of about 63–73 kDa. STS catalyzes the hydrolysis of the sulfate esters of 3-hydroxy steroids, which are inactive transport or precursor forms of the active 3-hydroxy steroids. STS can cleave estrone sulfate (E1S) and DHEA sulfate (DHEAS) . STS is a potential target for the treatment of hormone-dependent diseases[1].

  • Subcellular Localization

    Cytoplasmic vesicle, secretory vesicle, microneme membrane,Endoplasmic reticulum membrane

  • Isoforms & Post-Translational Modification

    P08842: 583 amino acids, molecular weight 65492 Da.

  • Subunit

    Homodimer

  • SwissProt ID

    P08842

  • Synonyms

    ARSC antibody

References

[1]. M J Reed, et al. Steroid sulfatase: molecular biology, regulation, and inhibition. Endocr Rev. 2005 Apr;26(2):171-202. [Content Brief]

Steroid sulfatase Antibody (YA6938) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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