SULT2B1 Antibody (YA7160)

Cat. No.: HY-P87473: Data Sheet User Guide for Antibodies
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SULT2B1 Antibody (YA7160) is a Mouse-derived and non-conjugated IgG1, Kappa monoclonal antibody, targeting to SULT2B1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SULT2B1 Antibody (YA7160) is a Mouse-derived and non-conjugated IgG1, Kappa monoclonal antibody, targeting to SULT2B1.

Host

Mouse

Clonality

Monoclonal,Recombinant

Molecular Weight

Predicted band size: 41kDa;

Species Reactivity

Human

SwissProt ID

O00204

Immunogen

Recombinant human SULT2B1.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000

Sensitivity	Endogenous	Purity	affinity purified by Protein G
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1, k

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol (PubMed:12145317, PubMed:19589875). Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA) (PubMed:12145317, PubMed:16855051, PubMed:21855633, PubMed:9799594). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA (PubMed:12145317, PubMed:21855633). Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation (PubMed:28575648)|Sulfonates pregnenolone but not cholesterol

Subcellular Localization：Cytoplasm, cytosol,Microsome,Nucleus

Expression：
Tissue_Specificity: Expressed in the stratum granulosum-stratum corneum junction in the skin (at protein level) (PubMed:28575648). Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung (PubMed:9799594)

Isoforms & Post-Translational Modification：O00204 has two isomers: O00204-1: 41308 Da (predicted); O00204-2: 39599 Da (predicted).
Phosphorylated

Documentation

User Guide for Antibodies (1077 KB)