SULT2B1 Antibody (YA7160)
(Synonyms: HSST2, SULT2B1, Sulfotransferase 2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family 2B member 1, Sulfotransferase family cytosolic 2B member 1, ST2B1)SULT2B1 Antibody (YA7160) is a Mouse-derived and non-conjugated IgG1, Kappa monoclonal antibody, targeting to SULT2B1.
-
Host:
Mouse
-
Isotype:
IgG
-
Application:
WB
-
Reactivity :
Human
-
Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-2000 |
Product Details
SULT2B1 Antibody (YA7160) is a Mouse-derived and non-conjugated IgG1, Kappa monoclonal antibody, targeting to SULT2B1.
-
Host Mouse
-
Clonality Monoclonal,Recombinant
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 41kDa;
Recombinant human SULT2B1.
Endogenous
affinity purified by Protein G
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
SULT2B1 is a Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation |Sulfonates pregnenolone but not cholesterol[1][2][3][4][5][6].
-
Subcellular Localization
Cytoplasm, cytosol,Microsome,Nucleus
-
Expression
Tissue_Specificity: Expressed in the stratum granulosum-stratum corneum junction in the skin (at protein level) (PubMed:28575648). Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung (PubMed:9799594) -
Isoforms & Post-Translational Modification
O00204 has two isomers: O00204-1: 41308 Da (predicted); O00204-2: 39599 Da (predicted).
Phosphorylated -
SwissProt ID
-
Synonyms
HSST2, SULT2B1, Sulfotransferase 2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family 2B member 1, Sulfotransferase family cytosolic 2B member 1, ST2B1
Documentation
Powered by Bioz
