SUPT16H Antibody (YA7888)(PBS only)

Cat. No.: HY-P88204A: Data Sheet User Guide for Antibodies
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SUPT16H Antibody (YA7888) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SUPT16H.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SUPT16H Antibody (YA7888) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SUPT16H.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y5B9

Immunogen

Human recombinant protein fragment corresponding to amino acids 187-282 of human SUPT16H produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II)

Subcellular Localization：Nucleus,Chromosome

Expression：
Tissue_Specificity: Ubiquitous

Isoforms & Post-Translational Modification：Q9Y5B9: 1047 amino acids, molecular weight 119914 Da.

Subunit：Interacts with MYOG (via C-terminal region) (By similarity)

Synonyms

CDC68; FACTP140; SPT16; SPT16/CDC68

Documentation

User Guide for Antibodies (1077 KB)