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  4. Monoclonal Antibodies Recombinant Antibodies
  5. TARC/CCL17 Antibody (YA1211)

TARC/CCL17 Antibody (YA1211)

Cat. No.: HY-P81466
User Guide for Antibodies Technical Support

TARC/CCL17 Antibody (YA1211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TARC/CCL17.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈 가격 재고 수량
20 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   견적 받기  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 제품 설명

제품 설명

TARC/CCL17 Antibody (YA1211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TARC/CCL17.
Host

Rabbit
Clonality

Recombinant,Monoclonal
분자량
Predicted band size: 11 kDa;
Observed band size: 11 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant protein of human TARC
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
100-1:200
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes (PubMed:8702936, PubMed:9169480). Acts by binding to CCR4 at T-cell surface (PubMed:10540332, PubMed:9169480). Mediates GM-CSF/CSF2-driven pain and inflammation (PubMed:27525438). In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation (By similarity). Plays a role in wound healing, mainly by inducing fibroblast migration into the wound (By similarity)
Subcellular Localization：Secreted
Expression：
Tissue_specificity:Constitutively expressed in thymus. Detected at lower levels in the lung, colon and small intestine (PubMed:8702936) . Expressed in stimulated peripheral blood mononuclear cells, but not in resting cells (PubMed:8702936)

Induction:In monocytes, up-regulated by IL4 and by GM-CSF/CSF2 in an IRF4-dependent manner (at protein level)
Database

Entrez Gene: 6361 Human

SwissProt: Q92583 Human

OMIM: 601520 Human

Research Field

Immunology
Synonyms
TARC; CCL17; SCYA17; C-C motif chemokine 17; C-C motif chemokine 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine
각종 서류
User Guide for Antibodies (1077 KB)

TARC/CCL17 Antibody (YA1211) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
TARC/CCL17 Antibody (YA1211)
Cat. No.:
HY-P81466
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