TBX1 Antibody (YA7754)(PBS only)

Cat. No.: HY-P88070A: Data Sheet User Guide for Antibodies
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TBX1 Antibody (YA7754) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TBX1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TBX1 Antibody (YA7754) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TBX1.

Host

Mouse

Molecular Weight

Predicted band size: 43 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O43435

Immunogen

Full length human recombinant protein of human TBX1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:4000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcription factor that plays a key role in cardiovascular development by promoting pharyngeal arch segmentation during embryonic development (By similarity). Also involved in craniofacial muscle development (By similarity). Together with NKX2-5, acts as a regulator of asymmetric cardiac morphogenesis by promoting expression of PITX2 (By similarity). Acts upstream of TBX1 for the formation of the thymus and parathyroid glands from the third pharyngeal pouch (By similarity). Required for hair follicle stem cell self-renewal (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (PubMed:11111039, PubMed:22095455)

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：O43435 has three isomers: O43435-1: 43133 Da (predicted); O43435-2: 40353 Da (predicted); O43435-3: 52666 Da (predicted).

Subunit：Binds DNA as a dimer (PubMed:11111039, PubMed:22095455)

Synonyms

CAFS; CATCH22; CTHM; DGCR; DGS; DORV; TBX1C; TGA; VCF; VCFS

Documentation

User Guide for Antibodies (1077 KB)